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Interaction With Other PDE Inhibitors PDEs are considered to be major mediators of cross talk between different second-messenger signaling pathways,15 eg, cGMP is known to inhibit PDE3, which hydrolyzes cAMP, thereby resulting in enhanced cAMP levels.
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PubMed Link to Article Figures Place holder to copy figure label and captionEnrollment, Randomization, and Follow-up of the Study ParticipantsThe number of patients screened and assessed for eligibility was not recorded.
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Critical revision of the manuscript for important intellectual content: Pisansky, Pugh, Greenberg, Pervez, Reed, Rosenthal, Mowat, Raben, Buyyounouski, Kachnic, Bruner.
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